LIST OF SEEDS UNDER OUR SUPPORT

1 Development of a novel and highly effcient RNAviral drug for treatment of peripheral arterial disease R&D Laboratory for Innovative Biotherapeutics, Graduate School of Pharmaceutical Sciences, Kyushu University
2 Therapeutics for intractable retinal degenerative disorders using novel lentiviral vectors developed in Japan Department of Ophthalmology, Kyushu University Hospital
3 Establishment of immunotherapy for refractorymalignant solid tumors using immuno-activatedRNA virus Department of Pediatric Surgery, Kyushu University Hospital
4 Bionic blood-pressure stabilization system forspinal cord injury patients Department of Cardiovascular Medicine, Kyushu University Hospital
5 Innovative less invasive therapeutic arteriogenesis induced by nanoparticle-mediated endothelial cell-selective drug delivery system Department of Surgery and Science, Kyushu University Hospital
6 Clinical research of High Density Mesenchymal stem cell scafold free Autologous Construct (HDMAC) derived from adipose for osteochondral regeneration Graduate School of Science and Engineering, Saga University
Department of Orthopaedic Surgery, Kyushu University Hospital
7 R&D in statin encapsulated PLGA nanoparticles for pulmonary hypertension Department of Cardiovascular Medicine, Kyushu University Hospital
8 Development of Brilliant Blue G (BBG) as a new surgical dye for internal limiting membrane (ILM) staining and peeling in vitrectomy Department of Ophthalmology, Kyushu University Hospital
9 Development of dendritic cell vaccine drugs based on the effcient cell expansion technology against intractable malignancies Department of Surgery and Science, Kyushu University Hospital
10 Autologous hematopoietic stem celltransplantation for severe systemic sclerosis Department of Hematology/Oncology, Department of Clinical Immunology and Rheumatology/Infectious Diseases, Kyushu University Hospital
11 Development of nucleic acid medicine targeting angiogenic factor: YB-1 for treatment of refractory cancer and proliferative vascular diseases Innovation Center for Medical Redox Navigation, Kyushu University
12 Novel antimitotic antineoplastic compounds with carbazole and benzohydrazide structures Department of Cellular Biochemistry, Graduate School of Pharmaceutical Sciences, Kyushu University
13 Development of periostin molecular targetingtherapy based on nkRNA(R) (novel class of RNA interference) technology Department of Ophthalmology, Kyushu University Hospital
14 Ex vivo generation of highly purified and activated NK cells (ZNK:zenithal natural killer cell)from human peripheral blood R&D Laboratory for Innovative Biotherapeutics, Graduate School of Pharmaceutical Sciences, Kyushu University
15 Development of liver regenerative medicine for children with functional three-dimensional liver structure using stem cells from human exfoliated deciduous teeth Department of Pediatric Surgery, Kyushu University Hospital
16 Efficacy of autologous adipose-derived mesenchymal stem cells on neuronal recovery in patients with ischemic stroke Department of Medicine and Clinical Science, Gradate School of Medical Sciences, Kyushu University
17 Nanotechnology-mediated drug delivery system to ischemia-reperfusion myocardium for treatment of reperfusion injury in acute myocardial infarction Department of Cardiovascular Medicine, Kyushu University Hospital
18 Non-contact magnetic vagus nerve stimulation system that reduces infarct size and mortality in patients with acute myocardial infarction Department of Cardiovascular Medicine, Kyushu University Hospital
19 Repositioning of the anti-chronic hepatitis drug 3-oxygermylpropionic acid polymer for inhibition of cancer metastasis Division of Cell Biology, Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University
Department of Surgery, Kyushu University Beppu Hospital
20 Physician-led phase II clinical study of OCV-C01 as a combination therapy of peptide-based cancer vaccines for patients with advanced biliary tract cancer refractory to priortherapy Department of Advanced Molecular and Cell Therapy, Kyushu University Hospital
21 A randomized control study to evaluate the prevention of recurrence and the safety of BCG (Bacillus Calmette-Guerin) instillation therapies between induction alone and induction + low-dose maintenance in non-muscle invasive bladder cancer Department of Urology Graduate School of Medical Sciences, Kyushu University
22 Method for predicting hepatic CYP3A4 activity from DNA methylation in peripheral blood cells Pharmaceutical Sciences Kyushu University
23 The usage of HMG-CoA reductase inhibitor to overcome cisplatin resistant cancers Department of Occupational Pneumology Institute of Industrial Ecological Sciences, University of Occupational and Environmental Health, Japan
24 Drug development of cerebral insufficiency improver for Alzheimer and vascular dementia Tohoku University Graduate School of Pharmaceutical Sciences
25 Developing new drug candidates for Niemann-Pick disease type C Department of Cell Modulation, IMEG, Kumamoto University
26 Development of the novel oncolytic coxsackievirus therapy for the clinical trial Department of Advanced Molecular and Cell Therapy, Kyushu University Hospital
27 Phase I study of cisplatin plus pemetrexed combined with salazosulfapyridine targeting cancer stem cells in advanced non-squamous non-small-cell lung cancer Department of Respiratory Medicine, Kyushu University Hospital
Division of Gene Regulation, Institute for Advanced Medical Research, School of Medicine, Keio University
28 Development and Clinical Evaluation of a Noninvasive Measuring Device for Oxygen Saturation Level in Retinal Vessels Saga University Hospital Department of Ophthalmology
29 c-Fos/AP-1 inhibitor as an intervention for the joint destruction in rheumatoid arthritis, the progression of systemic sclerosis, and the fatal outcome of sepsis Department of Medicine, Rheumatic Disease Unit
30 Development of anticancer therapy for targeted destruction of intractable malignant tumors using recombinant vaccinia virus Tottori University Graduate School of Medicine
31 Clinical trial of combination use of clopidogrel sulfate, pitavastatin calcium and tocopherol acetate ester for the control of osteonecrosis of the femoral head secondary to the initial corticosteroid treatment in patients with systemic lupus erythematosus Department of Orthopedics, Kyushu University Hospital
32 A novel combination vaccine therapy that targets disease-causing virus specific antigens for previously treated patients with adult T cell leukemia Department of Hematology, Kyushu Cancer Center
33 Phase I/II study of the HB-EGF-specific inhibitor BK-UM plus weekly paclitaxel therapy in gastric cancer with peritoneal metastasis after failure of first line treatment Department of Gastrointestinal Surgery, Kyushu University Hospital
34 Safety and efficacy of transcatheter closure of paravalvular leaks Department of Hematology/Oncology, Kyushu University Hospital